For shorter trips consider Greenville, Greensboro, and Asheville as potential places to explore. All can be options to fly to and are within 121 km of Florence, South Carolina.
Travelers looking to get as far as possible can consider Rome, Munich, and Frankfurt am Main as potential destinations for their travel.
The most popular destinations from Florence, South Carolina this month are Las Vegas, Miami, Newark Airport. The top year-round destinations include Las Vegas, New York, San Diego.